Dakin Reaction is a redox reaction in which an ortho or para-hydroxylated benzaldehyde or ketone reacts with hydrogen peroxide in alkaline conditions to form a benzenediol and a carboxylate ion.
In short, the oxidation of aldehydes or ketones to the corresponding phenol is known as the Dakin reaction.
Mechanism of Dakin reaction
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(1) Dakin reaction is used to synthesize catechol. Catechol is used as the starting material for the synthesis of several catecholamines, catecholamine derivatives, and 1, 4- tertbutyl catechol, a common antioxidant, and polymerization inhibitor.
(2) Dakin’s solution is a dilute hypochlorite solution. Chlorine, the active ingredient in Dakin’s solution, is a strong antiseptic that kills most forms of bacteria and viruses that may lead to skin and tissue infections.
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