Electrophilic Substitution in Naphthalene
Electrophilic Substitution in Naphthalene: The aromatic compounds like naphthalene, anthracene and phenanthrene are called polycyclic aromatic compounds because …
Pharmaceutical Organic Chemistry
Theory of Orientation
Theory of Orientation: Out of two important factors that govern the reactivity of aromatic rings towards an electrophile, …
Aromatic Electrophilic Substitution
Aromatic Electrophilic Substitution: Benzene possesses a planar structure involving an sp² hybrid orbital of six carbon atoms. Each …
Huckel’s Rule
Huckel’s Rule: Aromaticity is used to describe a cyclic, planar molecule with a ring of resonance bonds that …
Resonance of Benzene
Resonance of Benzene: Resonance or mesomerism describes oscillations of delocalized electrons within a molecule which is usually represented …
Claisen Schmidt Condensation
The condensation of an aromatic aldehyde with an aliphatic aldehyde or ketone in the presence of a base …
Schmidt Rearrangement
Schmidt Rearrangement reaction was discovered by Karl Friedrich Schmidt in 1924. Azides (RN3) are nucleophilic at their terminal …
Beckmann Rearrangement
Beckmann rearrangement is an acid-catalyzed rearrangement of an oxime to an amide. It is named after the German …
Dakin Reaction
Dakin Reaction is a redox reaction in which an ortho or para-hydroxylated benzaldehyde or ketone reacts with hydrogen …
Oppenauer Oxidation
Oppenauer Oxidation reaction is named after Rupert Viktor Oppenauer. This method is used for selectively oxidizing secondary alcohols …